Are dcpaminergic pathways involved in theory of mind? A study in Parkinson's disease
Identifieur interne : 002206 ( Main/Exploration ); précédent : 002205; suivant : 002207Are dcpaminergic pathways involved in theory of mind? A study in Parkinson's disease
Auteurs : Julie Peron [France] ; Siobhan Vicente [France] ; Emmanuelle Leray [France] ; Sophie Drapier [France] ; Dominique Drapier [France] ; Renaud Cohen [France] ; Isabelle Biseul [France] ; Tiphaine Rouaud [France] ; Florence Le Jeune [France] ; Paul Sauleau [France] ; Marc Verin [France]Source :
- Neuropsychologia [ 0028-3932 ] ; 2009.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
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Abstract
The "orbitofrontal" and "cingulate" frontostriatal loops and the mesolimbic dopaminergic system that modulates their function have been implicated in theory of mind (ToM). Parkinson's disease (PD) provides a model for assessing their role in humans. Results of the handful of previous studies of ToM in PD providing preliminary evidence of impairment remain controversial, mainly because the patients included in these studies were not accurately described, making it difficult to determine whether their ToM deficits were due to general cognitive deterioration or to a more specific dopaminergic deficit. The aim of our study was therefore to re-examine previous results highlighting ToM in PD and to explore the involvement of the dopaminergic pathways in ToM. ToM was investigated in 17 newly diagnosed PD patients (early PD group), 27 PD patients in the advanced stages of the disease (advanced PD group) and 26 healthy matched controls (HC), using two ToM tasks: a visual one, which is thought to reflect the "affective" ToM subcomponent ("Reading the Mind in the Eyes"), and a verbal one, which is thought to reflect both the "affective" and the "cognitive" ToM subcomponents (faux pas recognition). Furthermore, the early PD group was studied in two conditions: with and without dopamine replacement therapy (DRT). We failed to find any significant difference in ToM between the early PD patients and the HC group. Furthermore, there was no difference between the early PD patients in the medicated and unmedicated conditions. Conversely, the advanced PD patients scored poorly on the intention attribution question ("cognitive" ToM score) in the faux pas recognition task. The present results suggest that the deficit in ToM only occurs in the more advanced stages of the disease. In addition, our results would appear to indicate that these advanced PD patients present "cognitive" ToM impairment rather than global ("cognitive" and "affective") ToM impairment. In other words, the ToM deficit would appear to be present in PD patients where the degenerative process has spread beyond the dopaminergic pathways, but not in early PD patients where neuronal loss is thought to be restricted to the nigrostriatal and mesolimbic dopaminergic systems. In conclusion, our results suggest that the dopaminergic pathways are not involved in ToM.
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"Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Verin">Marc Verin</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Clinique Neurologique, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement 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A study in Parkinson's disease</title><author><name sortKey="Peron, Julie" sort="Peron, Julie" uniqKey="Peron J" first="Julie" last="Peron">Julie Peron</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Clinique Neurologique, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Vicente, Siobhan" sort="Vicente, Siobhan" uniqKey="Vicente S" first="Siobhan" last="Vicente">Siobhan Vicente</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Clinique Neurologique, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>S.H.U. Psychiatrie Adulte, CH Guillaume Régnier, 108 Avenue du Général Leclerc</s1><s2>35703 Rennes</s2><s3>FRA</s3><sZ>2 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Leray, Emmanuelle" sort="Leray, Emmanuelle" uniqKey="Leray E" first="Emmanuelle" last="Leray">Emmanuelle Leray</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Service d'Epidémiologie et de Santé Publique, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Drapier, Sophie" sort="Drapier, Sophie" uniqKey="Drapier S" first="Sophie" last="Drapier">Sophie Drapier</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Clinique Neurologique, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Drapier, Dominique" sort="Drapier, Dominique" uniqKey="Drapier D" first="Dominique" last="Drapier">Dominique Drapier</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Service d'Epidémiologie et de Santé Publique, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Cohen, Renaud" sort="Cohen, Renaud" uniqKey="Cohen R" first="Renaud" last="Cohen">Renaud Cohen</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Département de Psychologie, Ile du Saulcy, Université Paul Verlaine</s1><s2>57045 Metz</s2><s3>FRA</s3><sZ>6 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Lorraine (région)</region><settlement type="city">Metz</settlement></placeName></affiliation></author><author><name sortKey="Biseul, Isabelle" sort="Biseul, Isabelle" uniqKey="Biseul I" first="Isabelle" last="Biseul">Isabelle Biseul</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Rouaud, Tiphaine" sort="Rouaud, Tiphaine" uniqKey="Rouaud T" first="Tiphaine" last="Rouaud">Tiphaine Rouaud</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Clinique Neurologique, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Le Jeune, Florence" sort="Le Jeune, Florence" uniqKey="Le Jeune F" first="Florence" last="Le Jeune">Florence Le Jeune</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Service de Médecine Nucléaire, Centre Eugène Marquis, Rue de la Bataille Flandres Dunkerque</s1><s2>35042 Rennes</s2><s3>FRA</s3><sZ>9 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Sauleau, Paul" sort="Sauleau, Paul" uniqKey="Sauleau P" first="Paul" last="Sauleau">Paul Sauleau</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Clinique Neurologique, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Verin">Marc Verin</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Clinique Neurologique, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Recherche Universitaire 425 "Comportement et Noyaux Gris Centraux", Université Rennes 1, Hôpital Pontchaillou, CHU de Rennes, Rue Henri Le Guilloux</s1><s2>35033 Rennes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Neuropsychologia</title><title level="j" type="abbreviated">Neuropsychologia</title><idno type="ISSN">0028-3932</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Neuropsychologia</title><title level="j" type="abbreviated">Neuropsychologia</title><idno type="ISSN">0028-3932</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Dopamine</term><term>Emotion emotionality</term><term>Human</term><term>Parkinson disease</term><term>Theory of mind</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Théorie esprit</term><term>Maladie de Parkinson</term><term>Emotion émotivité</term><term>Dopamine</term><term>Homme</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The "orbitofrontal" and "cingulate" frontostriatal loops and the mesolimbic dopaminergic system that modulates their function have been implicated in theory of mind (ToM). Parkinson's disease (PD) provides a model for assessing their role in humans. Results of the handful of previous studies of ToM in PD providing preliminary evidence of impairment remain controversial, mainly because the patients included in these studies were not accurately described, making it difficult to determine whether their ToM deficits were due to general cognitive deterioration or to a more specific dopaminergic deficit. The aim of our study was therefore to re-examine previous results highlighting ToM in PD and to explore the involvement of the dopaminergic pathways in ToM. ToM was investigated in 17 newly diagnosed PD patients (early PD group), 27 PD patients in the advanced stages of the disease (advanced PD group) and 26 healthy matched controls (HC), using two ToM tasks: a visual one, which is thought to reflect the "affective" ToM subcomponent ("Reading the Mind in the Eyes"), and a verbal one, which is thought to reflect both the "affective" and the "cognitive" ToM subcomponents (faux pas recognition). Furthermore, the early PD group was studied in two conditions: with and without dopamine replacement therapy (DRT). We failed to find any significant difference in ToM between the early PD patients and the HC group. Furthermore, there was no difference between the early PD patients in the medicated and unmedicated conditions. Conversely, the advanced PD patients scored poorly on the intention attribution question ("cognitive" ToM score) in the faux pas recognition task. The present results suggest that the deficit in ToM only occurs in the more advanced stages of the disease. In addition, our results would appear to indicate that these advanced PD patients present "cognitive" ToM impairment rather than global ("cognitive" and "affective") ToM impairment. In other words, the ToM deficit would appear to be present in PD patients where the degenerative process has spread beyond the dopaminergic pathways, but not in early PD patients where neuronal loss is thought to be restricted to the nigrostriatal and mesolimbic dopaminergic systems. In conclusion, our results suggest that the dopaminergic pathways are not involved in ToM.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Grand Est</li><li>Lorraine (région)</li><li>Région Bretagne</li></region><settlement><li>Metz</li><li>Rennes</li></settlement></list><tree><country name="France"><region name="Région Bretagne"><name sortKey="Peron, Julie" sort="Peron, Julie" uniqKey="Peron J" first="Julie" last="Peron">Julie Peron</name></region><name sortKey="Biseul, Isabelle" sort="Biseul, Isabelle" uniqKey="Biseul I" first="Isabelle" last="Biseul">Isabelle Biseul</name><name sortKey="Cohen, Renaud" sort="Cohen, Renaud" uniqKey="Cohen R" first="Renaud" last="Cohen">Renaud Cohen</name><name sortKey="Drapier, Dominique" sort="Drapier, Dominique" uniqKey="Drapier D" first="Dominique" last="Drapier">Dominique Drapier</name><name sortKey="Drapier, Dominique" sort="Drapier, Dominique" uniqKey="Drapier D" first="Dominique" last="Drapier">Dominique Drapier</name><name sortKey="Drapier, Sophie" sort="Drapier, Sophie" uniqKey="Drapier S" first="Sophie" last="Drapier">Sophie Drapier</name><name sortKey="Drapier, Sophie" sort="Drapier, Sophie" uniqKey="Drapier S" first="Sophie" last="Drapier">Sophie Drapier</name><name sortKey="Le Jeune, Florence" sort="Le Jeune, Florence" uniqKey="Le Jeune F" first="Florence" last="Le Jeune">Florence Le Jeune</name><name sortKey="Le Jeune, Florence" sort="Le Jeune, Florence" uniqKey="Le Jeune F" first="Florence" last="Le Jeune">Florence Le Jeune</name><name sortKey="Leray, Emmanuelle" sort="Leray, Emmanuelle" uniqKey="Leray E" first="Emmanuelle" last="Leray">Emmanuelle Leray</name><name sortKey="Leray, Emmanuelle" sort="Leray, Emmanuelle" uniqKey="Leray E" first="Emmanuelle" last="Leray">Emmanuelle Leray</name><name sortKey="Peron, Julie" sort="Peron, Julie" uniqKey="Peron J" first="Julie" last="Peron">Julie Peron</name><name sortKey="Rouaud, Tiphaine" sort="Rouaud, Tiphaine" uniqKey="Rouaud T" first="Tiphaine" last="Rouaud">Tiphaine Rouaud</name><name sortKey="Rouaud, Tiphaine" sort="Rouaud, Tiphaine" uniqKey="Rouaud T" first="Tiphaine" last="Rouaud">Tiphaine Rouaud</name><name sortKey="Sauleau, Paul" sort="Sauleau, Paul" uniqKey="Sauleau P" first="Paul" last="Sauleau">Paul Sauleau</name><name sortKey="Sauleau, Paul" sort="Sauleau, Paul" uniqKey="Sauleau P" first="Paul" last="Sauleau">Paul Sauleau</name><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Verin">Marc Verin</name><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Verin">Marc Verin</name><name sortKey="Vicente, Siobhan" sort="Vicente, Siobhan" uniqKey="Vicente S" first="Siobhan" last="Vicente">Siobhan Vicente</name><name sortKey="Vicente, Siobhan" sort="Vicente, Siobhan" uniqKey="Vicente S" first="Siobhan" last="Vicente">Siobhan Vicente</name><name sortKey="Vicente, Siobhan" sort="Vicente, Siobhan" uniqKey="Vicente S" first="Siobhan" last="Vicente">Siobhan Vicente</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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